Scott City is a city in Cape Girardeau and Scott counties in the state of Missouri. The population was 4,565 at the 2010 census. The Scott County portion of Scott City (the majority) is part of the Sikeston Micropolitan Statistical Area, while the Cape Girardeau County portion is part of the Cape Girardeau–Jackson, MO-IL Metropolitan Statistical Area.
The town of Fornfelt and the area of Ancell were consolidated with Scott City on March 7, 1960 and Illmo, Missouri, was incorporated into Scott City in 1980. The town of Fornfelt was previously known as Edna, but this name was changed as it was too similar to Edina, Missouri. Whipporwhill Hollow was the previous name of Illmo. The present name is derived from Scott County.
Scott City R-I School District operates Scott City Elementary School, Scott City Middle School, and Scott City High School. Scott City has a public library, a branch of the Riverside Regional Library.